Wash your hands and vegetables. Clean your cooking area.
Combine chili powder, cumin, onion powder, garlic powder, dried oregano, and paprika in a small bowl.
Heat a large non-stick skillet over medium-high. Add turkey; cook 5 minutes or until browned, stirring to crumble. Sprinkle with spice mixture; cook 1 minute or until fragrant, stirring constantly. Add water (if needed); cook 4 minutes or until thickened and meat is done.
Heat taco shells according to package directions.
Fill shells evenly with turkey filling, lettuce, tomato, avocado, and cheese.